Dr. Bruce H. McCormick establishes the Scientific Visualization Laboratory, the predecessor of the Brain Networks Laboratory.
The lab receives an NSF Major Research Instrumentation grant (#0079874). Design of the KESM instrument begins.
Assembly of KESM begins.
KESM assembly and control interface software complete. Polymerization algorithm for 3D reconstruction developed.
First KESM data become available (Golgi). Nissl and Golgi sections obtained. Use of white light source.
Presentation of KESM progress at the Computational Neuroscience meeting in Alicante, Spain. C elegans web experimental studies.
Presentation of KESM progress at the Annual Society for Neuroscience Meeting's satellite symposium on "Images as Phenotypes", sponsored by the National Institute of Mental Health Human Brain Project (by invitation).
Design of second-generation KESM begun. The goal is to abate knife chatter and increase data bandwidth (in collaboration with Prof. Marian Wiercigroch at the University of Aberdeen, UK).
A reinforced knife and collimator mount has been designed and installed on the first generation KESM, which greatly improved resistence to chatter.
Code development of fully automated sectioning and imaging begins. Design for the second generation KESM (KESM 2.0) begins.
Near completion of fully automated sectioning and imaging software. KESM 2.0 design continues (optics).
Completion of fully automated sectioning and imaging software. Sectioning of large volumes of mouse brain tissue begins. KESM 2.0 design mostly complete.